Lichen simplex chronicus (LSC) also known Neurodermatitis. It is a stubborn skin disorder featurised by chronic itching and scratching. Few skin types are more prone to lichenification, means skin that tends toward eczematous conditions (ie, atopic dermatitis, atopic diathesis). Central and peripheral neural tissue and inflammatory cell products in the process of itch and ensuing changes in LSC.

The possible interplay among primary blisters, psychic factors, and the intensity of pruritus additively influences the limit and harshness of LSC. Ultimately, the affected skin becomes thick and leathery. LSC is present on the skin in regions operable to scratching. Pruritus provokes friction that produces clinical blisters, but the underlying pathophysiology is unknown.LSC occurs mainly in mid-to-late adulthood, with highest prevalence in persons aged 30-50 years. LSC is observed more in females as compared to males.

Lichen simplex chronicus is seen near the ankles, shins and the back or side of the neck. The forearms may also be fully involved. Lichen simplex chronicus is normally caused by continous rubbing of the skin. Lichen nuchae is a kind of lichen simplex which occurs on the midposterior neck and is marked almost exclusively in women. The rubbing begins the chain of occurances that leads from itching to scratching and then to the presence of leather-like skin patches. Lichen simplex chronicus is generally caused by constant rubbing of the skin.

Symptoms are harmful itching which is accompanied by nervous tension. The appearance of scratch marks and the leathery skin patches can be found anywhere on the body parts. Chronic lichen simplex chronicus results in pigmentation which is brown is colour at the site of irritation.

Causes of Lichen Simplex Chronicus

Common causes of Lichen Simplex Chronicus

• Constant rubbing of the skin.
• Insect bites.
• Scars (eg, traumatic, postherpetic/zoster).
• Acne keloidalis nuchae.
• Venous insufficiency.
• Asteatotic.
• Psychological factors( Anxiety and Neurodermatitis).
• Lithium.
• Eczema.

Symptoms of Lichen Simplex Chronicus

Common Symptoms of Lichen Simplex Chronicus

• Itching.
• Skin lesion.
• Lesions.
• Anxiety.
• Stress.
• Inflammation.

Treatment of Lichen Simplex Chronicus

Common Treatment of Lichen Simplex Chronicus

• Occlusion also deliver a physical barrier to the scratching. Midpotency topical steroids are not helpful for thin skin (eg, vulva, scrotum, axilla, face).
• Direct long-term therapy more at daily use of low-potency nontrophogenic topical corticosteroids.
• Antihistamines such as diphenhydramine (Benadryl) and hydroxyzine (Atarax) are common.
• Doxepin (Sinequan) and clonazepam (Klonopin) may be considered in appropriate cases.
• Other topical medications reported to decrease pruritus include doxepin cream and capsaicin cream.
• Aspirin/dichloromethane is effective in patients with LSC..
• Used in directing the changes in cellular activity that induce itching and inflammation.
• Avoid things that increase itching.