Pityriasis lichenoides is a rare skin affecting disorder. It ia chronic form and also known as pityriasis lichenoides chronica (PLC). Pityriasis lichenoides encircles a spectrum of clinical presentations ranging from acute papular lesions. Blisters may self-intricate and resolve fully over weeks, or new lesions occasionally may appear in crops, waxing and waning spontaneously for months to years. thereafter. Historically, the term Mucha-Habermann disease has directed only to PLEVA, the term applies in general to the entire spectrum of disease including PLC. A rare feverish ulceronecrotic variant has been described, which is a severe form of PLEVA with high fever and marked inborn symptoms. The majority of cases present in adolescence or early adulthood. PLEVA making way to the theory that the disorder represents a relatively benign form of lymphoproliferative disease. Fibrin is not present in the walls of vessels, and thrombi are not found in the lumen.
Some children are also affected with a form of the disease which frequently resolves spontaneously. Symptoms that happens in the childhood age suggest that it may follow a virus infection. It is more common in males than females. Neither kind of pityriasis lichenoides is infectious Mucha-Habermann disease is not a lymphoproliferative illness. CD30(Ki-1) cells, which are usually connected with large cell lymphoma, have been pointed in blisters of patients with PLC and A cell-mediated mechanism has been intended based on a T-lymphocytic infiltrate with a cytotoxic/suppressor phenotype, diminished epidermal Langerhans cells, and a reduction of the CD4/CD8 ratio.
Causes of Pityriasis Lichenoides
Common causes of Pityriasis Lichenoides
- Mucha-Habermann disease.
- Pityriasis rosea.
- Acute lichen planus.
- Guttate psoriasis.
- Erythema multiforme.
- Toxoplasma gondii titers.
Symptoms of Pityriasis Lichenoides
Common Symptoms of Pityriasis Lichenoides
- Fever.
- Lethargy.
- Myalgia.
- Central necrosis.
- Haemorrhagic crusts.
- Itching.
- Burning of affected areas
- Lesions.
- Scarring.
Treatment of Pityriasis Lichenoides
Common Treatment of Pityriasis Lichenoides
- Corticosteroid creams and ointments applied to the skin often control the rash and itching.
- Antihistamines such as Benadryl by mouth will help alleviate the itching.
- Sometimes ultraviolet light treatment will improve pityriasis lichenoides.
- Sunburn should be avoided.
- Oral antibiotics used are erythromycin and tetracycline . These antibiotics have been used to treat both PLC and PLEVA.
- Phototherapy treatment with UVB or PUVA has been used with varying success both in patients with PLEVA and in those with PLC.