Bio breakthrough in skin penetration means better results when it comes to using a vitamin k treatment on spider veins or varicose veins. There are leg spider veins, face spider veins, nose spider veins and much more including the breast. There is a difference between spider and varicose veins and while both repsond well it is the spider vein that typically just has the appearance of the veins on the legs, face, arms, breasts and nose as the most common places. These spider veins usually do not have much discomfort with them while varicose veins can be accompanied by swelling of the legs and veins as well as aching and pains especially if you have been standing all day long. The best topical solution is a vitamin k cream yet most vitamin k particles are so large that they never actually penetrate the skin to get to the vein. Vitamin K works by helping to clot the blood that is leaking from the exterior veins. This in turn alleviates the appearance of the spider veins and often times the varicose veins. When looking for a spider veins cream make sure to get a bio pepetide cream as they ingredients are much smaller and penetrate better.